![]() Reproduced with permission from Science Museum Group, London. ![]() Depiction of a 19th century ‘laughing gas party’. Doctor Syntax and his wife making an experiment in pneumatics. ![]() 2,3Įase of access and the common misperception of a ‘safe high’ has led to an increase in abuse and consequent neurological morbidity among young Australians.įigure 1. 1 Before any medical application, it became popular at upper class ‘laughing gas parties’ (Figure 1) and public variety performances, where audience members were invited on stage to inhale the gas and entertain the crowd with disinhibited song and dance. It was first isolated in 1772 by the English scientist, philosopher and theologian Joseph Priestley. Nitrous oxide is a familiar gas in medicine, with both analgesic and anaesthetic properties.
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